Nightlife districts represent unique environments for police, requiring a specialized approach. Yet documentation was limited on this unique focus area of public safety and policing. In response, RHI produced this comprehensive guide in cooperation with police input and based upon a decade of research and collection of practices among police departments worldwide. This guide contains ten sections highlighting nighttime public safety practices in officer selection, recruitment incentives, deployment strategies, specialized training topics, application of CPTED and SARA, as well as data collection for data-driven decision making in nightlife settings. The guide has been presented at Major Cities Chiefs Association and is also available in Spanish.